Computing infrastructure for the definition, performance testing and implementation of safe-by-design approaches in nanotechnology supply chains

EUflag white low ID 6256 NanoUptake project has received funding from the European Union’s HORIZON 2020 research and innovation programme under grant agreement n°862195.

Project duration: 01 04 2020 - 31 03 2024 (48 months)

Total cost: EUR 5.979.609,99

EU contribution: EUR 5.979.609,99

Number of partners: 23 beneficiaries

BNN members participating in NanoUptake: none

Coordinator: Instituto Tecnologico del Embalaje, Transporte y Logistica (Valencia, Spain)

Project keywords: nanotechnology, nano-materials, nano engineering

Project summary & objectives:

A major challenge for the global nanotechnology sector is the development of safe and functional engineered nanomaterials (ENMs) and nano-enabled products (NEPs). In this context, the application of the Safe-by-Design (SbD) concept has been adopted recently by the nanosafety community as a means to dampen human health and environmental risks, applying preventive safety measures during the design stage of a facility, process, material or product. However and despite its importance, SbD prescriptions are still in their infancy, and are hampered among other things by the lack of comprehensive data about the performance, hazard and release potential of the great variety of NEPs in use.

NanoUptake addresses that problem creating a comprehensive new e-infrastructure to foster dialogue and collaboration between all actors in the supply chain for a knowledge-driven definition of SbD setups that optimize hazard, technical performance and economic costs. Our project developes a validated rapid hazard profiling module, coupled to a new exposure-driven modelling framework to reduce toxicity. This safe-born material also undergoes a cost-benefit analysis algorithm to find the best compromise between safety and a industrially convenient technical performance. Finally, a new software interface where product information can be exchanged between the supply chain participants is the tool that wraps up, finishing the collaborative spirit of NanoUptake between regulators, researchers and industry. Coherently with its goals, our NanoUptake project is international and open-scienced in essence, with the clear aim of impacting the EU policies as well as directly and clearly benefiting the citizen.


Role of BNN:

BNN will lead all activities related to stakeholder engagement, as well as dissemination and exploitation of project results. In addition, BNN will contribute to developing the e-infrastructure for a well-balanced Safe-by-Design approaches selection. Moreover, BNN will support positioning of the project on international level, connecting and liaising with its network of contacts in the nanotech field (e.g., EU NanoSafety Cluster).



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